By Elliott L. Mancall MD, David G. Brock MD CIP
ISBN-10: 1416047050
ISBN-13: 9781416047056
Gray's medical Neuroanatomy makes a speciality of how understanding sensible neuroanatomy is vital for a pretty good neurologic history for sufferer care in neurology. Elliot Mancall, David Brock, Susan Standring and Alan Crossman current the authoritative tips of Gray's Anatomy besides a hundred scientific situations to focus on the relevance of anatomical wisdom during this physique quarter and illustrate the rules of localization. grasp complicated, specified, and tough parts of anatomy with self belief. View illustrations from Gray's Anatomy and radiographs that depict this physique quarter in thorough anatomical aspect. observe the rules of localization because of a hundred short case experiences that spotlight key medical stipulations. faucet into the anatomical authority of Gray's Anatomy for top of the range details from a reputation you belief. offers the suggestions and services of a excessive profile staff of authors and most sensible medical and educational individuals.
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Additional resources for Gray's Clinical Neuroanatomy: The Anatomic Basis for Clinical Neuroscience
Sample text
26 Pacinian corpuscle in transverse section, showing the central core region and lamellar cells surrounding the axon. Note the presence of large intercellular spaces between the lamellar cells and the numerous mitochondria in the axon (Rhesus monkey finger). (Material provided by W. ) Chapter 2 / Overview of the Microstructure of the Nervous System Chapter 2 Fig. 27 Structure and innervation of a Golgi tendon organ. For clarity, the perineurium and endoneurium have been omitted to show the distribution of nerve fibres ramifying between the collagen fibre bundles of the tendon.
Afferent fibres from free terminals may be myelinated or unmyelinated but are always of small diameter and low conduction velocity. When afferent axons are myelinated, their terminal arborizations are not. These terminals serve several sensory modalities. In the dermis, they may be responsive to moderate cold or heat (thermoreceptors); light mechanical touch (mechanoreceptors); damaging heat, cold or deformation (unimodal nociceptors) and damaging stimuli of several kinds (polymodal nociceptors).
In chemoreceptors, receptor action may resemble that for ACh at neuromuscular junctions. Visual receptors share similarities with chemoreceptors: light causes changes in receptor proteins, which activate G-proteins, resulting in the release of second messengers, and this affects membrane permeability. The quantitative responses of sensory endings to stimuli vary greatly and increase the flexibility of sensory systems’ functional design. Although increased excitation with an increasing stimulus level is a common pattern (‘on’ response), some receptors respond to decreased stimulation (‘off ’ response).