By Dieter Kaufmann
ISBN-10: 3805585209
ISBN-13: 9783805585200
The neurofibromatoses are autosomal-dominant genetic problems of the worried process that basically impact the improvement and development of neural mobile tissue. those problems reason tumors to develop on nerves and convey different abnormalities comparable to dermis alterations and bone deformities. in recent times, the genes and mutations inflicting neurofibromatoses were pointed out. the most different types of neurofibromatoses, style 1 (NF1) and sort 2 (NF2), were proven to be certain issues either clinically and genetically. extra lately, allelic and non-allelic subtypes of NF1 were outlined in addition to the NF2-related schwannomatosis. a few of the complicated molecular mechanisms resulting in the neurofibromatoses were elucidated, leading to a turning out to be physique of guides that are tough to maintain with. This quantity offers a massive evaluate of contemporary findings at the neurofibromatoses. It makes a speciality of the genetics and molecular biology underlying those illnesses, but in addition covers their medical positive factors, prognosis and therapy, stressing the necessity for interdisciplinary treatment. With contributions by means of the most important investigators within the box, this well timed ebook will attract geneticists, genetic counselors, pediatricians, neurologists and oncologists.
Read Online or Download Neurofibromatoses PDF
Best neurosurgery books
Musculoskeletal Diseases: Diagnostic Imaging and Interventional Techniques
This ebook represents a condensed model of the 20 subject matters facing imaging analysis and interventional remedies in musculoskeletal ailments. The disease-oriented subject matters surround the entire appropriate imaging modalities together with X-rays expertise, nuclear medication, ultrasound and magnetic resonance, in addition to image-guided interventional suggestions.
Erythropoietin and the Nervous System
Erythropoietin (EPO) is a chemokine hormone that's greatly disbursed through the physique. as well as its conventional position as a hormone that stimulates pink blood cellphone creation, in recent times many laboratories have proven that EPO can act as a neuroprotective compound in a number of damage paradigms within the fearful procedure.
Percutaneous Vertebroplasty is a concise and updated reference that information the necessities for constructing a contemporary scientific lab, opting for sufferers, adequately acting the method and heading off pitfalls which are ordinarily encountered. Over ninety five pictures, especially created for this ebook, give you the reader with exact examples of ways each one point of the approach is played in an comprehensible step-by-step layout.
Electroceuticals: Advances in Electrostimulation Therapies
This publication covers fresh advances within the use of electrostimulation cures in move issues, epilepsy, inflammatory bowel affliction, reminiscence and cognition, problems of recognition, foot drop, dysphagia, mind harm, headache, middle failure, listening to loss, and rheumatoid arthritis. It describes suggestions akin to vagus nerve stimulation, deep mind stimulation, and electric stimulation of the pharyngeal nerve.
- Handbook on Cerebral Artery Dissection
- Handbook of Neurosurgery
- Complications in Head and Neck Surgery with CD Image Bank, 2e
- Think Big: Unleashing Your Potential for Excellence
Extra resources for Neurofibromatoses
Example text
Watson GH: Pulmonary stenosis, café-au-lait spots, and dull intelligence. Arch Dis Child 1967;42:303–307. Partington MW, Burggraf GW, Fay JE, Frontini E: Pulmonary stenosis, café au lait spots and dull intelligence: the Watson syndrome revisited. Proc Greenwood Genet Center 1985;4:105 (abstract).
Currently, there are two main options: the Iliazarov procedure as one treatment approach or alternatively, treatment by transfer of a vascularized fibular graft from the contralateral extremity. Recently, successful treatment was reported by applicating recombinant human bone morphogenetic protein [13]. Scoliosis Monitoring of the spine is an important task of the follow-up examinations. Patients with clinical evidence of incipient scoliosis need close intervals Mautner/Boltshauser 24 for monitoring the progression of scoliosis (months).
This new treatment form is based on receptor tyrosine kinase inhibitors such as STI 571 (Imatinib). The first clinical trials investigating the therapeutic benefit of receptor tyrosine kinase inhibitors in MPNST have been initiated [25]. Mautner/Boltshauser 28 Vascular Problems Hypertension occurs in association with NF1 and may have several different causes, including pheochromocytoma (2%) and renal artery stenosis (2%). The renal artery stenosis is one manifestation of a vasculopathy that can occur localized or generalized [26].