By Peter Gerszten, Samuel Ryu
ISBN-10: 162623034X
ISBN-13: 9781626230347
ISBN-10: 1626230358
ISBN-13: 9781626230354
Spine Radiosurgery, moment Edition, is a accomplished textual content that comes with discussions of the most recent units, remedy making plans recommendations, objective definition, and sufferer choice during this area of expertise. Written via top specialists within the fields of neurosurgery, radiation oncology, and clinical physics, this publication is the definitive reference for scientific purposes of state of the art radiosurgery of the spine.
Key Features:
- Six new chapters on such issues as histopathological exam of spinal lesions, minimally invasive options, and therapy of spinal chordomas
- More than a hundred full-color illustrations demonstrate
key concepts
- Discussion of recent remedies for metastatic backbone disorder and spinal wire compression
This e-book is a must have source for clinicians, fellows, and citizens in neurosurgery and radiation oncology. backbone surgeons, orthopaedists, scientific physicists, and oncologists in any respect degrees also will enjoy the wealth of data provided.
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Extra info for Spine Radiosurgery
Sample text
Radiation tolerance of rat spinal cord to pulsed dose rate (PDR-) brachytherapy: the impact of differences in temporal dose distribution. Radiother Oncol 2000; 55: 301–315 [33] Pop LA, van der Plas M, Ruifrok AC, Schalkwijk LJ, Hanssen AE, van der Kogel AJ. Tolerance of rat spinal cord to continuous interstitial irradiation. Int J Radiat Oncol Biol Phys 1998; 40: 681–689 [34] Pop LA, van der Plas M, Skwarchuk MW, Hanssen AE, van der Kogel AJ. High dose rate (HDR) and low dose rate (LDR) interstitial irradiation (IRT) of the rat spinal cord.
Two approaches to the modeling of complications in normal tissue are the following: (1) phenomenologic models, in which the goal is to describe the tissue response without a theory of the causal explanation by using the smallest number of parameters possible; and (2) mechanistic models, in which one attempts to dissect the dose–response relationship into constituent components based on current knowledge of the functional tissue architecture. An ideal model attempts to relate radiation dose mechanistically in a quantitative way to an observed effect by considering the physical absorbed dose, the geometric dose distribution, the tissue radiosensitivity, and the temporal delivery pattern.
Br J Radiol 1961; 34: 246–251 [61] Withers HR, Taylor JM, Maciejewski B. Treatment volume and tissue tolerance. Int J Radiat Oncol Biol Phys 1988; 14: 751–759 [62] Niemierko A, Goitein M. Modeling of normal tissue response to radiation: the critical volume model. Int J Radiat Oncol Biol Phys 1993; 25: 135–145 [63] Schultheiss TE. The controversies and pitfalls in modeling normal tissue radiation injury/damage. Semin Radiat Oncol 2001; 11: 210–214 3 Clinical Spinal Cord Tolerance to Radiosurgery 3 Clinical Spinal Cord Tolerance to Radiosurgery Simon S.