By John Joseph Fenton
ISBN-10: 0849303710
ISBN-13: 9780849303715
REAL-LIFE circumstances, instructional QUESTIONS, NARRATIVE HISTORY
Intriguing anecdotal pedagogy, just like the alleged arsenical poisonings of Napoleon and President Taylor and the possible mercury overdose of Isaac Newton, is likely one of the issues that set Toxicology: A Case-Oriented process except different toxicology texts. in accordance with an undergraduate-graduate mixed toxicology direction at West Chester college, this leading edge textual content captures readers' curiosity through combining glossy case stories, ancient circumstances, and 1000's of illustrations and tables. every one bankruptcy provides a number of case situations that contain the reader with questions on analysis, checking out tools, remedy, and different pertinent info.
TOXICOLOGY FOR THE LABORATORY AND THE EMERGENCY ROOM
In an easy-to-read kind, this ebook covers the most important organ platforms and studies the consequences of poisons in every one procedure. such a lot modern books are nearly completely medical or totally analytical. Toxicology: A Case-Oriented technique treats each one zone commonly to learn scholars and execs who want to know elements of either. It describes prognosis and remedy of every particular toxic publicity and discusses chemical foundation and the laboratory trying out of poisons. This twin viewpoint, coupled with the book's fascinating narrative procedure, shall we readers speedy soak up the knowledge they should comprehend toxicology within the laboratory and within the Emergency division.
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Extra info for Toxicology : a case-oriented approach
Sample text
One ppb is intuitively less concentrated than 1 ppm by a factor of 1000. Therefore, if 1 ppm equals 1 mg/L we expect that 1 ppb will equal 1 mg/L divided by 1000 or 1 µg/L. , are understood to represent 1 molecule per million molecules of air, one molecule per billion molecules of air, and so on. , are not based on weight. 9 mole gas EXAMPLE For sulfur dioxide, the molecular weight is 64 g/mole. 9 µg/m3 1 ppm on a molecule basis is, as shown above, equal to 2617 µg/m3 The latter answer is, by convention, taken to be correct.
Basic drugs such as tricyclic antidepressants or phencyclidine can be excreted more rapidly by acidifying the urine. This is not recommended, however, because the benefits of improved elimination usually are more than offset by the deleterious effects of the blood acidosis on cardiac and CNS function. 1). In dialysis the various substances in blood will diffuse across into the dialysis bath provided that they are small enough (low molecular weight) to transit the membrane and their concentration is lower in the bath than in blood.
Uncommon drugs such as chlorpheniramine may be misidentified. 9% for marijuana metabolite. These data show that drug quantitation is conducted with excellent accuracy with coefficients of variation (CV) being generally low; for example, 96% of the labs testing cocaine metabolite gave results within 18% of an average value of 373 mcg/mL. It may legitimately be concluded that drug-testing accuracy is good and much better than it was in the 1980s. Testing is of the highest quality for drugs that are the objects of frequent testing and is less accurate for uncommon drugs.