By Nicholas P. Cheremisinoff
"This beneficial source presents distinctive healthiness and security info at the damaging and poisonous houses of over 1,000 seriously used business and client chemical substances. Lists chemical substances either alphabetically and numerically in keeping with their Chemical summary carrier quantity allowing fast entry to express data!"
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Additional info for Dangerous Properties of Industrial and Consumer Chemicals
REPORT 10:EPA HEALTH ASSESSMENT DOC EPA- 600/8-86-014A DRAFTSEP 86 INADEQUATE EVIDENCE FOR MUTAGENICITY OR CHEMICAL INTERACTION WITH MAMMALIAN GERM CELLS. REPT’D USE:TEXTILE FINISHES, GLYCERIN PRODUCTION, MFG. COLLOIDAL FORMS OF METALS, PLASTICS AND PERFUMES, PRODUCTION OF ACRYLIC ACID/ESTERS AND SYNTHESIS OF METHIONINE BIOCIDECAS NO:7008-42-6CHEM NAME:*** ACRONYCINEREPORT 01:NCI CARC TRS 49 DHEW PUBNO NIH 78-849 ACRONYCINE GIVEN BY ABDOMINAL INJECTION CAUSED A VARIETY OF CANCERS IN MALE/FEMALE RATS.
CARCINOMA FROM RESPIRATORY EPITHELIUM FOUND IN TOP-DOSE RATS; NASAL CARCINOMA. REPORT 02:NTP TECHNICAL BULLETIN 9MAR 83 ACETALDEHYDE WAS NEGATIVE IN ONE SALMONELLA TYPHIMURIUM MUTAGENICITY ASSAY. Page 11 REPORT 03:IARC MONOGRAPH 36FEB 85 TESTED IN RATS BY INHALATION EXPOSURE AND IN HAMSTERS BY INHALATION EXPOSURE AND INTRATRACHEAL INSTILLATION. FOLLOWING INHALATION EXPOSURE, INCREASED INCIDENCE OF CARCINOMAS INDUCED IN NASAL MUCOSA OF RATS, AND LARYNGEAL CARCINOMAS INDUCED IN HAMSTERS. IN ANOTHER INHALATION STUDY IN HAMSTERS, USING LOWER EXPOSURE LEVEL, AND IN INTRATRACHEAL INSTILLATION STUDY, NO INCREASED INCIDENCE OF TUMORS OBSERVED.
THE COMPOUND WAS ADMINISTERED ORALLY AND BY INHALATION. A PRELIMINARY EPIDEMIOLOGICAL REPORT DEMONSTRATES AN INCREASED RISK OF CANCER OF THE LUNG AND THE LARGE INTESTINE IN WORKERS EXPOSED IN CERTAIN AREAS OF A TEXTILE FIBERS PLANT. 210XlHLDEC 80 SPRAGUE-DAWLEY RATS EXPOSED TO VAPOR CONCENTRATIONS OF 0, 20, OR 80 PPM OF ACRYLONITRILE FOR 24 MONTHS SHOWED STATISTICALLY SIGNIFICANT ADVERSE EFFECTS OF BOTH NON-TUMOROUS AND TUMOROUS NATURE. REPORT 05:MONSANTO ORAL TOXICITY AND CARCINOGENICITY STUDYDEC 80 ACRYLONITRILE, ADMINISTERED AT 10, 30 AND 100 PPM IN DRINKING WATER TO F344 RATS FOR 24 MONTHS, RESULTED IN AN Page 20 INCREASED INCIDENCE OF ASTROCYTOMAS OF THE CNS AND SQUAMOUS CELL CARCINOMAS IN THE EAR CANAL, AS WELL AS MAMMARY CARCINOMAS IN FEMALES RECEIVING 100 PPM.