By V. Rogiers, M. Pauwels, P. Itin, G.B.E. Jemec
ISBN-10: 3805586558
ISBN-13: 9783805586559
This quantity of «Current difficulties in Dermatology» provides the reader with a portrait of the clinical historical past of the advanced means of security review of cosmetics in addition to info on eu beauty laws. a pragmatic method of the hunt for toxicity facts on beauty constituents and a compilation of the legally required technical file of a entire beauty product in addition to an in-depth research of the protection overview of beauty constituents played on the ecu point through the clinical Committee on purchaser items (SCCP) can be found. the present prestige of 3R choices to animal checking out and the level to which they're applied by means of the beauty and regarded through the SCCP within the hazard evaluation method is discussed.As such, counsel is supplied relating to the manifold demanding situations beauty defense assessors are confronted with within the present ecu regulatory environment. during this necessary instruction manual, certified beauty protection assessors, providers of uncooked fabrics, dermatologists and pharmacists, toxicologists in addition to european officers and directors facing cosmetics will locate appropriate details at the ecu beauty laws, the compilation of beauty technical dossiers, toxicological database searches, and the supply and use of different equipment within the box of cosmetics.
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Additional resources for Safety Assessment of Cosmetics in Europe
Sample text
1907/2006 [EU, 2006a] concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals, commonly referred to as ‘REACH’, introduces some major changes in the EU regulatory framework for chemicals, among which: – The reversal of the burden of proof: manufacturers and/or importers become fully responsible for proving and ensuring that their substances are safe to use, whereas previously the Member States’ competent authorities equally expressed an approval for the safe use of the substance under consideration [Recitals 18, 25, 29, Art.
B) Relevance for Cosmetics Cleansing cosmetic products typically contain different kinds of surfactants which also form part of detergents. Human safety appearing to be of inferior importance in the assessment of these types of ingredients, only local health effects such as allergenicity and skin irritation, are addressed. Moreover, the only official data requirements 18 Rogiers и Pauwels involve labelling of known allergens, thus usually no new data are generated. This strongly reduces the impact of the Detergents Directive on the safety data availability of cosmetic ingredients.
The compilation of points a–h is commonly referred to as a cosmetic’s TIF or PIR. 5. The Annexes to the Cosmetic Products Directive and the SCC(NF)P Like the majority of EU Directives, Dir. 76/768/EEC is composed of the classical set of articles (definitions, responsibilities of the EU Member States, safeguard clause, . ), followed by a number of technical annexes. Five of them consist of ingredient lists: – Annex II: list of forbidden substances in cosmetic products. – Annex III: list of substances which are not allowed to be used in cosmetic products outside the restrictions and conditions laid down.