By Hans Hedrich
ISBN-10: 0123364256
ISBN-13: 9780123364258
Between animals utilized in examine, instructing and checking out, mice at the moment are widely known because the most vital version for human illnesses and issues. They include the vast majority of all experimental mammals and have a tendency to be the version of selection used for examine into many diseases/disorders together with melanoma, center sickness, bronchial asthma, Alzheimer's, Down syndrome, deafness, osteoporosis, weight problems, diabetes or even psychological overall healthiness learn. also the laboratory mouse keeps to play a greatly publicized very important function within the human genome project.One of the main time-consuming actions in learn laboratories is asking up info particular to the species or pressure of animal getting used. This e-book, a part of the hugely profitable guide of Experimental Animals sequence, permits the consumer easy accessibility to any focal point at the mouse as an experimental version. * Edited by means of Hans Hedrich, Hannover scientific university* finished reference resource written via overseas specialists* Well-illustrated with top of the range special photos* Two-color, effortless layout mixed with colour plate sections
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Extra resources for The Laboratory Mouse (Handbook of Experimental Animals)
Example text
1998). Nature 394, 369-374. Schonig, K. and Bujard, H. (2003). In Transgenic Mouse Methods and Protocols(eds M. Hofker and J. van Deursen), Watson, J. and Crick, E (1953). Nature 171,737-738. , pp. 69-104. Humana Press, Totowa, New Jersey. , Jaenisch, R. and Schimenti, J. (1997). M. (I 995). Mouse Genetics, Conceptsand Applications, Nat. Genet. 15, 285-288. pp. 3-31. Oxford University Press, New York. CHAPTER Strains, Stocks, and Mutant Mice ~2 Carol C Linder and Muriel T Davisson z ,-I The Jackson Laboratory, Bar Harbor, Maine, USA I m Introduction Genetically defined inbred mice are universally accepted as the principal model for analyzing and understanding inherited human disorders (Paigen, 1995, 2002; Davisson, 1999; Zambrowicz and Sands, 2003).
2003). http:/lwww. P. (1994). Science 264, 1329-1333. , Matin, A. S. (2000). Nat. Genet. 24, 221-225. H. A. (1984). Proc. Natl. Acad. Sci. A. 81,814-818. Nagy, A. (2000). Genesis26, 99-109. , Sandmeyer, S. and Plasterk, R. (2003). Nat. Genet. ), 276-284. I O UJ "r FLI.. M. S. (1995). Proc. Natl. Acad. Sci. USA 9 2 , 6592-6596. D. J. Genet. 49, 87. D. and Hunter, J. (2000). Nat. D. (1978). In Origim oflnbredMice, Proceedings of a Workshop, Bethesda, MD, February 1978 (ed. Genet. C. Morse, III), pp.
Spontaneous mutations usually lead to Robertsonian chromosomes, and insertions, exchanges the discovery of new genes, whereas targeted mutations I'1"1 of DNA segments between chromosomes; and (3) aneu- can be engineered only for those genes that already z ploidy, deviations from the normal diploid number of have been identified and cloned. g. trisomies). tions also are more likely to resemble the naturally _~ Some chromosomal deletions and duplications also may occurring mutations that cause human inherited disre"lbe cytologically detectable.