By A. A. Letavet, E. B. Kurlyandskaya
ISBN-10: 0080134149
ISBN-13: 9780080134147
The Toxicology of Radioactive ingredients, quantity five: Zinc-65 bargains with the poisonous homes of the radioisotope zinc-65 in addition to its organic results. Emphasis is put on the function of reliable zinc within the response of the physique to the management of zinc-65. a few of the result of laboratory experiences at the poisonous results of zinc-65 on animals, essentially rabbits, are offered.
This quantity is made out of 18 chapters and opens with an outline of sure facets of the toxicology of radioactive zinc-65, via a dialogue at the habit of zinc-65 within the rat physique. next chapters discover the distribution of zinc-65 within the physique of rabbits following persistent oral management; bioelectrical task of the cerebral cortex in rabbits in stipulations of lengthy management of radioactive zinc; the impact of lengthy inner irradiation with G5ZnCl2 at the practical country of the rabbit center; and points of hemopoiesis following power consumption of radiozinc. Morphological alterations in experimental animals following power publicity to radioactive zinc also are thought of.
This booklet could be of curiosity to chemists and toxicologists.
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Extra info for The Toxicology of Radioactive Substances. Volume 5
Example text
The two last diagrams relate to the period after administration of isotope had ceased. m i ii in iv m M i II in iv % i II m iv k i II iniv VI i i II in iv i II in iv 25/4 18/5 23/5 29/5 10-12/6 17/6 D 25 counts in apparatus with three gamma counters at a distance of 30 cm from centre of specimen FIG. 1. The time course of the level of activity in the body of rats receiving ,i5 Zn with different amounts of carrier. Explanation in text It will be seen that at all times irrespective of the level of activity a definite relation persisted between the four groups of rats receiving different doses of stable zinc.
5. The mean radiation doses absorbed by the rat body throughout the period of the experiment were 3-8, 3-6, 3*15 and 1-65 rad for intake of stable zinc of 0, 0-04, 0-4 and 2-0 mg/day per rat respectively. References AVRUNINA G. , Accumulation and Excretion of 60Co in Animals and Tissue Doses During Daily Oral Administration. In: The Toxicology of Radioactive Substances Vol. 2, p. 30 (Ed. Letavet A. A. and Kurlyandskaya E. ) Pergamon Press, Oxford (1963). AVRUNINA G. , Body Radiation Doses in Rabbits Produced by Daily Oral Adminis tration of 59FeCl3, and Some Data on Accumulation and Excretion of 59Fe.
Ter. 5, 75-82 (1960). M C K E N N E Y J. , MCCLELLAN R. O. and BUSTAD L. , Early Uptake and Dosimetry of Zn 65 in Sheep. Hlth. Phys. 8, 411 (1962). NESMEYANOV A. N . , LAPITSKII A. V. and RUDENKO N . , The Production of Radioactive Isotopes (Polucheniye radiokatvnykh izotopov). Moscow (1954). RUBANOVSKAYA A. A. and USHAKOVA V. , Accumulation of Radioactive Strontium in Young Rats Born to and Fed by Females Receiving Continuous Oral Administra tion of 89Sr or a Mixture of 89Sr and 90 Sr. I n : The Toxicology of Radioactive Substances, Vol.