By Richard M. Kostrzewa (eds.)
ISBN-10: 1461458358
ISBN-13: 9781461458357
ISBN-10: 1461458366
ISBN-13: 9781461458364
ISBN-10: 1461474582
ISBN-13: 9781461474586
The instruction manual of Neurotoxicity is a reference resource for determining, characterizing, teaching on use, and describing results of neurotoxin remedies – to appreciate mechanisms linked to toxin use; to undertaking results of neurotoxin remedies; to gauge neurotoxins as predictors of occasions resulting in neurodegenerative problems and as aids to rational use of neurotoxins to version ailment entities. Neuroprotection is approached in numerous manners together with these 1) afforded through healing brokers – scientific and preclinical; or 2) via non-drug capacity, corresponding to workout. The amorphous time period ‘neurotoxin’ is mentioned by way of the prospective eventuality of a neuroprotectant generating an end result of extra neuronal survival and a behavioral spectrum that will produce a disorder – such as a neurotoxin’s impression. The guide of Neurotoxicity is hence an instructive and worthwhile advisor in the direction of realizing the position of neurotoxins/neurotoxicity within the expansive box of Neuroscience, and is an fundamental device for laboratory investigators, neuroscientists, and scientific researchers.
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Extra info for Handbook of Neurotoxicity
Sample text
2 6-OHDA Analogs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 6-Hydroxydopa (6-OHDOPA) . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 DSP-4 and Xylamine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) . . . . . . . . . . . . . . . 6 Haloperidol-Related Chemical Species .
6 Haloperidol-Related Chemical Species . . . . . . . . . . . . . . . . . . . . . . . 7 20 -Amino-MPTP . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 5,6- and 5,7-Dihydroxytryptamine (5,6-DHT, 5,7-DHT) . . . . . . . . . . . . . . 9 Amphetamines . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 Excitatory Amino Acids . . . . . . . .
15 3-Nitropropionic Acid (3-NP) . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16 Toxic Vanilloids, TRPV1 Receptor Agonists . . . . . . . . . . . . . . . . . . . . 17 Botulinum Neurotoxin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18 Quinpirole, a Dopamine D2-Receptor Agonist . . . .