By National Council on Radiation Protection
ISBN-10: 0913392723
ISBN-13: 9780913392720
ISBN-10: 1435629485
ISBN-13: 9781435629486
Read Online or Download Induction of Thyroid Cancer by Ionizing Radiation (N C R P Report) PDF
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Extra info for Induction of Thyroid Cancer by Ionizing Radiation (N C R P Report)
Example text
69 cases per million person per rad per year for children and adults respectively. 05. In fact, no excess cancers were determined to be present. The calculation in the case of children is less certain due to the small numbers and lack of precise information regarding their actual spontaneous rate of thyroid cancer as they reach adult life. Thus, in summary, I3'I appears less carcinogenic in people on a radfor-rad basis than external radiation. How much less is yet to be determined; in fact, available human data on low dose 13'1 exposures have not shown 13'1 to be carcinogenic in the human thyroid.
6. 6-Thyroid cancer incidence for each registry-number of cases (both sexes) and age standardized rates per 100,000persons' Age Standard Rates/100,000 Total No. of Geographical Area Thyroid Cancers Male Female United States Alameda: White Black Bay Area: White Black Chinese Connecticut Iowa Detroit: White Black N. Mexico: Spanish Other White Amer. /Amer. /Asia Sweden Ja~an 'Age-standardized rates based on Waterhouse et al. (1976). on other factors such as species, genetic background, ethnic groups, environment, etc.
Choi (1978) and Feinstein (1977) have discussed mathematical models for predicting the minimum number of subjects required in a study of adverse effects characterized by an increased incidence of a spontaneously occurring abnormality. 05; Po is the proportion of cases in which thyroid cancer occurs naturally; and P is the proportion of cases in which thyroid cancer occurs after radiation, including spontaneous cases. 5 and Zp = 0) in order to approximate a central estimate analogous to the risk estimate calculation for external radiation.