Download Poisoning and Drug Overdose by Kent Olson PDF

By Kent Olson

ISBN-10: 0838581722

ISBN-13: 9780838581728

The simplest guide at the analysis and therapy of poisoning and drug overdose. completely up-to-date, this reference beneficial properties broad tables summarizing toxicity and place of work publicity instructions for over 500 commercial chemical substances, an index containing the components of over a hundred and fifty universal advertisement items, and tabs for speedy reference.

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AUTONOMIC SYNDROMESa,b Blood Pressure Pulse Rate Pupil Size Sweating Peristalsis Alpha-adrenergic + − + + − Beta-adrenergic ± + ± ± ± Mixed adrenergic + + + + − Sympatholytic − − -- − − Nicotinic + + ± + + Muscarinic − -- -- + + Mixed cholinergic ± ± -- + + Anticholinergic ± + + -- -- Key to symbols: + = increased; − = decreased; - - = markedly decreased; ± = mixed effect, no effect, or unpredictable. Adapted, with permission, from Olson KR et al: Med Toxicol 1987;2:54. qxd_cc 9/9/03 1:18 PM Page 30 30 POISONING & DRUG OVERDOSE 6.

2. 2°F). 3. Dystonia. 5–1 mg/kg IM or IV; or benztropine (Cogentin™; p 418), 1–4 mg IM in adults. Follow this treatment with oral therapy for 2–3 days. 4. Dyskinesia. Do not treat with anticholinergic agents. 2 mg/kg IM (p 415). 5. Rigidity. Do not treat with anticholinergic agents. Instead, administer a sedative (see item 4, directly above) or provide specific pharmacologic therapy as follows: a. Intravenous calcium (see p 424) or Latrodectus antivenom for a black widow spider bite (p 346). b.

Susman VL: Clinical management of neuroleptic malignant syndrome. Psychiatr Q 2001;72(4):325–336. ) OTHER COMPLICATIONS I. Dystonia, dyskinesia, and rigidity A. Assessment. Examples of drugs and toxins causing abnormal movements or rigidity are listed in Table I–15. 1. Dystonic reactions are common with therapeutic or toxic doses of many antipsychotic agents and with some antiemetics. The mechanism triggering these reactions is thought to be related to central dopamine blockade. Dystonias usually consist of forced, involuntary, and often painful neck rotation (torticollis), tongue protrusion, jaw extension, or trismus.

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